Radiative Neutralino Decay in Supersymmetric Models

The radiative decay Z2-> Z1 gamma proceeds at the one-loop level in the MSSM. It can be the dominant decay mode for the second lightest neutralino Z2 in certain regions of parameter space of supersymmetric models, where either a dynamical and/or kinematic enhancement of the branching fraction occurs. We perform an updated numerical study of this decay mode in both the minimal supergravity model (mSUGRA) and in the more general MSSM framework. In mSUGRA, the largest rates are found in the ``focus point'' region, where the mu parameter becomes small, and the lightest neutralinos become higgsino-like; in this case, radiative branching fraction can reach the 1% level. Our MSSM analysis includes a scan over independent positive and negative gaugino masses. We show branching fractions can reach the 10-100% level even for large values of the parameter tan(beta). These regions of parameter space are realized in supergravity models with non-universal gaugino masses. Measurement of the radiative neutralino branching fraction may help pin down underlying parameters of the fundamental supersymmetric model.Comment: 19 page JHEP file with 8 PS figures; previous version contained figure misplacemen

EDTA and Taurolidine Affect Pseudomonas aeruginosa Virulence In Vitro-Impairment of Secretory Profile and Biofilm Production onto Peritoneal Dialysis Catheters

Peritoneal catheter-associated biofilm infection is reported to be the main cause of refractory peritonitis in peritoneal dialysis patients. The application of antimicrobial lock therapy, based on results on central venous catheters, may be a promising option for treatment of biofilm-harboring peritoneal catheters. This study investigated the effects of two lock solutions, EDTA and taurolidine, on an in vitro model of Pseudomonas aeruginosa biofilm-related peritoneal catheter infection. Silicone peritoneal catheters were incubated for 24 h with a bioluminescent strain of P. aeruginosa. Then, serial dilutions of taurolidine and/or EDTA were applied (for 24 h) once or twice onto the contaminated catheters, and P. aeruginosa viability/persistence were evaluated in real time up to 120 h using a Fluoroskan reader. On selected supernatants, high-performance liquid chromatography mass spectrometry (HPLC-MS) analysis was performed to measure the production of autoinducers (AI), phenazines, and pyocyianines. Taurolidine alone or in combination with EDTA caused a significant decrease of bacterial load and biofilm persistence on the contaminated catheters. The treatment did not lead to the sterilization of the devices, yet it resulted in a substantial destructuration of the catheter-associated P. aeruginosa biofilm. HPLC-MS analysis showed that the treatment of biofilm-harboring catheters with taurolidine and EDTA also affected the secretory activity of the pathogen. EDTA and taurolidine affect P. aeruginosa biofilm produced on peritoneal catheters and profoundly compromise the microbial secretory profile. Future studies are needed to establish whether such lock solutions can be used to render peritoneal catheterrelated infections more susceptible to antibiotic treatment

A wearable multimodal interface for exploring urban points of interest

Locating points of interest (POIs) in cities is typically facilitated by visual aids such as paper maps, brochures, and mobile applications. However, these techniques require visual attention, which ideally should be on the surroundings. Non-visual techniques for navigating towards specific POIs typically lack support for free exploration of the city or more detailed guidance. To overcome these issues, we propose a multimodal, wearable system for alerting the user of nearby recommended POIs. The system, built around a tactile glove, provides audio-tactile cues when a new POI is in the vicinity, and more detailed information and guidance if the user expresses interest in this POI. We evaluated the system in a field study, comparing it to a visual baseline application. The encouraging results show that the glovebased system helps keep the attention on the surroundings and that its performance is on the same level as that of the baseline

The dilaton-dominated supersymmetry breaking scenario in the context of the non-minimal supersymmetric model

The phenomenological consequences of the dilaton-type soft supersymmetry breaking terms in the context of the next to minimal supersymmetric standard model are investigated. We always find a very low top quark mass. As a consequence such string vacua are excluded by recent experimental results. The viability of the solution of the $\mu$ term through the introduction of a gauge singlet field is also briefly discussed.Comment: 10 pages,LATE

SearchBot: Supporting voice conversations with proactive search

Searching during conversations and social interactions is becoming increasingly common. Although searching could be helpful for solving arguments, building common ground, and reinforcing mutual assumptions, it can also cause inter-actional problems. Proactive search approaches can enrich conversations with additional information without neglecting the shared and established social norms of being attentive to ongoing interaction. This demo showcases SearchBot, a tool that minimizes the issues associated with the practice of searching during conversations. It accomplishes this by tracking conversational background speech and then providing continuous recommendations of related documents and entities in a non-intrusive way [3]

An Action-Based Approach to Presence: Foundations and Methods

This chapter presents an action-based approach to presence. It starts by briefly describing the theoretical and empirical foundations of this approach, formalized into three key notions of place/space, action and mediation. In the light of these notions, some common assumptions about presence are then questioned: assuming a neat distinction between virtual and real environments, taking for granted the contours of the mediated environment and considering presence as a purely personal state. Some possible research topics opened up by adopting action as a unit of analysis are illustrated. Finally, a case study on driving as a form of mediated presence is discussed, to provocatively illustrate the flexibility of this approach as a unified framework for presence in digital and physical environment

Impact of R-Parity Violation on Supersymmetry Searches at the Tevatron

We evaluate cross sections for \eslt, 1$\ell$ and various dilepton and multilepton event topologies that result from the simultaneous production of all sparticles at the Tevatron collider, both within the minimal model framework as well as in two different $R$-parity violating scenarios. Our analysis assumes that these $R$-violating couplings are small, and that their sole effect is to cause the lightest supersymmetric particle to decay inside the detector. We reassess future strategies for sparticle searches at the Tevatron, and quantify by how much the various signals for supersymmetry could differ from their minimal model expectations, if $R$-parity is not conserved due to either baryon number or lepton number violating operators. We also evaluate the Tevatron reach in $m_{\tg}$ for the various models, and find that rate-limited multilepton signals ultimately provide the largest reach for both $R$-parity conserving and $R$-parity violating cases.Comment: preprint nos. FSU-HEP-941001, UR-1387, ER-40685-836 and UH-511-807-94, 13 pages (REVTEX) plus 3 uuencoded figures attache

A two-step, user-centered approach to personalized tourist recommendations

Geo-localized, mobile applications can simplify a tourist visit, making the relevant Point of Interests more easily and promptly discernible to users. At the same time, such solutions must avoid creating unfitting or rigid user profiles that impoverish the users' options instead of refining them. Currently, user profiles in recommender systems rely on dimensions whose relevance to the user is more often presumed than empirically defined. To avoid this drawback, we build our recommendation system in a two-step process, where profile parameters are evaluated preliminarily and separately from the recommendations themselves. We describe this two-step evaluation process including an initial survey (N=206), and a subsequent controlled study (N=24). We conclude by emphasizing the benefit and generalizability of the approach

Designing for Mixed Reality Urban Exploration

This paper introduces a design framework for mixed reality urban exploration (MRUE), based on a concrete implementation in a historical city. The framework integrates different modalities, such as virtual reality (VR), augmented reality (AR), and haptics-audio interfaces, as well as advanced features such as personalized recommendations, social exploration, and itinerary management. It permits to address a number of concerns regarding information overload, safety, and quality of the experience, which are not sufficiently tackled in traditional non-integrated approaches. This study presents an integrated mobile platform built on top of this framework and reflects on the lessons learned

Iron metabolism and lymphocyte characterisation during Covid-19 infection in ICU patients: An observational cohort study

Background: Iron metabolism and immune response to SARS-CoV-2 have not been described yet in intensive care patients, although they are likely involved in Covid-19 pathogenesis. Methods: We performed an observational study during the peak of pandemic in our intensive care unit, dosing D-dimer, C-reactive protein, troponin T, lactate dehydrogenase, ferritin, serum iron, transferrin, transferrin saturation, transferrin soluble receptor, lymphocyte count and NK, CD3, CD4, CD8 and B subgroups of 31 patients during the first 2 weeks of their ICU stay. Correlation with mortality and severity at the time of admission was tested with the Spearman coefficient and Mann-Whitney test. Trends over time were tested with the Kruskal-Wallis analysis. Results: Lymphopenia is severe and constant, with a nadir on day 2 of ICU stay (median 0.555 109/L; interquartile range (IQR) 0.450 109/L); all lymphocytic subgroups are dramatically reduced in critically ill patients, while CD4/CD8 ratio remains normal. Neither ferritin nor lymphocyte count follows significant trends in ICU patients. Transferrin saturation is extremely reduced at ICU admission (median 9%; IQR 7%), then significantly increases at days 3 to 6 (median 33%, IQR 26.5%, p value 0.026). The same trend is observed with serum iron levels (median 25.5 μg/L, IQR 69 μg/L at admission; median 73 μg/L, IQR 56 μg/L on days 3 to 6) without reaching statistical significance. Hyperferritinemia is constant during intensive care stay: however, its dosage might be helpful in individuating patients developing haemophagocytic lymphohistiocytosis. D-dimer is elevated and progressively increases from admission (median 1319 μg/L; IQR 1285 μg/L) to days 3 to 6 (median 6820 μg/L; IQR 6619 μg/L), despite not reaching significant results. We describe trends of all the abovementioned parameters during ICU stay. Conclusions: The description of iron metabolism and lymphocyte count in Covid-19 patients admitted to the intensive care unit provided with this paper might allow a wider understanding of SARS-CoV-2 pathophysiology